- Zoar Outdoor
 - Whitewater rafting, canoe and kayak instruction, trips and rock climbing clinics in southern New England. - Zero Gravity Corporation (ZERO-G)
- Offering weightless flights aboard a specially modified Boeing 727-200 aircraft from Fort Lauderdale-Hollywood International Airport.
- Zephyr Whitewater Expeditions
- Offers whitewater rafting adventures on the Kings, Tuolumne, and Merced Rivers near Yosemite, California.
- Zegrahm Expeditions
- Expeditions to the outer reaches of the world. All programmes are limited in size and lead by distinguished naturalist and lecturers.
- Zero Gravity Corporation
- Offers parabolic flights in a modified Boeing 727 to give passengers the experience of weightlessness.
- Zambezi Safari and Travel Company
- Specialises in safaris throughout Africa from top tourist spots to remote bush camps.
- Zoller's Outdoor Odysseys
- Whitewater trips on the White Salmon River of the Columbia River Gorge in Washington State.
- Zenith Travel
- Tour operator offering all inclusive cruises to the Galapagos Islands aboard sailboats and private yachts. Zenith also offers trip extensions to the Amazon and Andes of Ecuador and Peru.
- Zurko International
- Offers European tours visiting antique markets, collectors fairs, bazaars, flea markets, and more.
- Zingela Safaris
- Offers hunting safaris in Southern Africa and at Gras Hunting Ranch in Nambia.
- Zeus Tours
- Tour operator and yacht cruise specialist, with programmes in Greece, the Mediterranean, Italy, Turkey, Israel, and Egypt.
- Zanzibar Magic
- Offering tours, safaris, sightseeing, accommodation, and flights to Zanzibar and Tanzania.
- Zolo Trips
- Global active travel packages including Asian holidays in Myanmar, Tibet, Cambodia, and Vietnam, adventure tours, Nepal trekking, and more.
- Zion Waterside Retreat
- Centre for small conference groups, private retreats, workshops, seminars, and corporate events.
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