- Active Pass Pharmaceuticals
 - Biotechnology company researching and developing drugs for the treatment of Alzheimer's. - Adherex Technologies
- Focused on the development of therapeutic products based on its proprietary cell adhesion technology.
- Aegera Therapeutics Inc.
- Specialises in the discovering and development of novel therapies for neurodegenerative diseases, nerve injuries, and cancer.
- Angiotech Pharmaceuticals
- Developing treatments for cancer, arthritis, and other diseases characterized by inappropriate cell proliferation and blood vessel growth.
- BioAtlantech
- Encourages biotech firms to take advantage of the opportunities created by R&D activities in the province.
- BioMS Medical
- Offers synthetic peptide technology which has the potential to help chronic progressive multiple sclerosis patients.
- BioNova
- Association of companies and institutions involved in the biotechnology and life science industries.
- BioQuebec
- Supports the growth and vitality of the province's biotechnology companies.
- Cardiome Pharma Corp.
- Drug discovery and development company focused on developing proprietary drugs to treat or prevent cardiac diseases. Formerly Nortran Pharmaceuticals.
- Cedarlane Laboratories
- Manufacturer and distributor of research reagents, such as antibodies, low-tox complement, and lympholyte cell separation media.
- Forbes Medi-Tech
- Engaged in the research and development of pharmaceutical and nutraceutical products for the prevention and treatment of cardiovascular and related diseases.
- Generex Biotechnology
- Developing technologies for oral delivery of large-molecule drugs.
- Hemosol, Inc.
- Biopharmaceutical company developing a multi-product pipeline based on proprietary technologies in the field of blood cells and proteins.
- HepaLife
- Focuses on research, development, and commercialization of technologies and products to treat liver dysfunction and disease.
- ID Biomedical Corporation@
- Immucon
- Contraception and fertility biotech company.
- Inex Pharmaceuticals Corporation
- Biopharmaceutical company commercializing drugs that utilize the company's proprietary drug delivery systems to treat cancer.
- International Medical Innovations
- Develops tests that detect diseases, focusing on cardiovascular disease and cancer.
- L.A.M. Pharmaceutical Corp.
- Developing transdermally delivered therapeutic prescription and over-the-counter drugs.
- Lorus Therapeutics Inc.
- Focused on the development of cancer therapies.
- Micrologix Biotech
- Discovers, develops, and commercializes drugs to treat life-threatening diseases, focusing on solutions to the antibiotic resistance crisis.
- Oncolytics Biotech
- Discovers and develops pharmaceutical products for the treatment of cancers that have not been successfully treated with conventional therapeutics.
- PharmaGap Inc.
- Specialises in 3-dimensional cell-based screening assays, analytical software, and gap junction intercellular communications therapeutics.
- Procyon Biopharma, Inc.
- Focused on the R&D of cancer therapies derived from antinuclear auto-antibody (ANA) and prostate secretory protein (PSP94) technologies.
- Sussex Research Laboratories Inc.
- Develops proprietary carbohydrate-based synthetic technologies for drug and vaccine research, discovery, and development.
- Vasogen
- Research and commercial development of immune modulation therapies targeting the chronic inflammation underlying cardiovascular and neuro-inflammatory diseases.
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